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Last updated: 2016/12/4
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LRRK2 polyclonal antibody

  • Catalog # : PAB12701
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LRRK2.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human LRRK2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 285
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes ~285 KDa of human LRRK2.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.1-1 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.2 (BSA, 10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The cell lysate derived from NIH/3T3 was immunoprobed by LRRK2 polyclonal antibody (Cat # PAB12701) at 1 : 500. An immunoreactive band is observed around ~285 kDa (1). This band is abolished by pre-incubation with immunizing peptide (2).
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Gene Name:
  • LRRK2
  • Gene Alias:
  • AURA17,DARDARIN,PARK8,RIPK7,ROCO2
  • Gene Description:
  • leucine-rich repeat kinase 2
  • Gene Summary:
  • This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq
  • Other Designations:
  • Parkinson disease (autosomal dominant) 8,augmented in rheumatoid arthritis 17
  • Gene Pathway
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