Product Browser

Last updated: 2016/9/25
  • Related Product Showcase

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

LRP6 polyclonal antibody

  • Catalog # : PAB12700
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LRP6.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids (KGTYF) of human LRP6.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 180
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes ~180 KDa of human LRP6.
  • Form:
  • Liquid
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (0.1-1 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.2 (BSA, 10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The cell lysate derived from NIH/3T3 was immunoprobed by LRP6 polyclonal antibody (Cat # PAB12700) at 1 : 500. An immunoreactive band is observed around ~180kDa (1). This band is abolished by pre-incubation with immunizing peptide (2).
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4040
  • Gene Name:
  • LRP6
  • Gene Alias:
  • ADCAD2,FLJ90062,FLJ90421
  • Gene Description:
  • low density lipoprotein receptor-related protein 6
  • Gene Summary:
  • The LRP6 gene encodes a member of the low density lipoprotein receptor (LDLR) gene family, which consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDLR proteins are comprised of the same basic structural motifs: an extracellular domain that contains LDLR binding repeats and EGF repeats with associated spacer domains containing the YWTD motif; a single transmembrane-spanning domain; and a C-terminal cytoplasmic domain that generally contains at least 1 copy of the NPXY motif (Brown et al., 1998 [PubMed 9704021]). LRP6 and LRP5 (MIM 603506) function as coreceptors for WNT (MIM 164820) ligands and thus play a role in WNT signaling, which is important in a wide variety of biologic processes during pre- and postnatal life in invertebrates and vertebrates (Kokubu et al., 2004 [PubMed 15469977]).[supplied by OMIM
  • Other Designations:
  • low density lipoprotein-related protein 6
  • Gene Pathway
  • RSS
  • YouTube
  • Linkedin
  • Facebook