The cell lysate derived from NIH/3T3 cells was immunoprobed by JUN polyclonal antibody (Cat # PAB12669) at 1 : 500. An immunoreactive band is observed around ~48kDa (Lane 1). This band is blocked by pre-incubation with immunizing peptide (Lane 2).
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq
Jun activation domain binding protein,OTTHUMP00000010036,activator protein 1,enhancer-binding protein AP1,v-jun avian sarcoma virus 17 oncogene homolog,v-jun sarcoma virus 17 oncogene homolog