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Last updated: 2016/12/4
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AR polyclonal antibody

  • Catalog # : PAB12653
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AR.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding S210 of human AR.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 110
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes ~110 KDa of human AR.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.1-1 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    Immunohistochemistry (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.2 (BSA, 10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Dot Blot (Peptide)
  • Dot Blot (Peptide)
  • Dot Blot : 1 ug peptide was blot onto NC membrane.
    A : AR (pS210).
    B : AR (Non-phospho).
    Folowed were blotted at a 1 : 2000 dilution by :
    1. Phospho-AR S210 polyclonal antibody (Cat # PAB12654).
    2. AR polyclonal antibody (Cat # PAB12653).
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 367
  • Gene Name:
  • AR
  • Gene Alias:
  • AIS,DHTR,HUMARA,KD,NR3C4,SBMA,SMAX1,TFM
  • Gene Description:
  • androgen receptor
  • Gene Summary:
  • The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023450,OTTHUMP00000061928,dihydrotestosterone receptor
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