The cell lysate derived from Conditioned NIH/3T3 cell was immunoprecipitated by ROCK2 (phospho T396) polyclonal antibody (Cat # PAB12643), then immunoprobed by the same antibody at 1 : 500 (lane 1). Lane 2 is a negative control.
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq