Western blot analysis of MLXIPL in liver nuclear extracts from well-fed rats. 7% SDS gel, 1 : 1,000 dilution of MLXIPL polyclonal antibody (Cat # PAB12520). Photo courtesy of Dr. Uyeda, UT Southwestern University.
Western Blot (Cell lysate)
Western blot analysis of MLXIPL in 20 ug of human hepatocyte lysate using MLXIPL polyclonal antibody (Cat # PAB12520). 5-10 second film exposure.
Immunofluorescent staining of MLXIPL in human hepatocyte using MLXIPL polyclonal antibody (Cat # PAB12520). Overlay staining of MLXIPL (rhodamine red) and DAPI nuclear staining (blue).
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq
Mlx interactor,OTTHUMP00000160457,OTTHUMP00000160458,WS basic-helix-loop-helix leucine zipper protein,Williams Beuren syndrome chromosome region 14,carbohydrate response element binding protein,carbohydrate-responsive element-binding protein