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Last updated: 2016/12/4
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ABCG8 polyclonal antibody

  • Catalog # : PAB12501
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ABCG8.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human ABCG8.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • Specific for ABCG8.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of ABCG8 using ABCG8 polyclonal antibody (Cat # PAB12501). Samples : mouse liver microsomes from G5/G8 knockout mice (lane 1), wildtype human G5/G8 (Lane 2), and transgenic human G5/G8 (lane 3).
  • Application Image
  • Gene Information
  • Gene Name:
  • ABCG8
  • Gene Alias:
  • GBD4,MGC142217,STSL
  • Gene Description:
  • ATP-binding cassette, sub-family G (WHITE), member 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette sub-family G member 8,ATP-binding cassette, subfamily G, member 8,sterolin 2
  • Gene Pathway
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