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Last updated: 2021/6/20
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ATP7B polyclonal antibody 

  • Catalog # : PAB12478
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ATP7B.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human ATP7B.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to ATPb7.
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunocytochemistry/Immunofluorescence (1:10-1:2000)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    This antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot. By WB, this antibody recognizes a band at 165 kDa, representing ATP7b. This antibody also recognizes a band at ~220 kDa. This antibody may work on endogenous protein in immunohistochemistry, but it has only been tested on transfected ovarian carcinoma cells at a 1:500 dilution. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 540
  • Gene Name:
  • ATP7B
  • Gene Alias:
  • PWD,WC1,WD,WND
  • Gene Description:
  • ATPase, Cu++ transporting, beta polypeptide
  • Gene Summary:
  • This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq
  • Other Designations:
  • ATPase, Cu(2+)- transporting, beta polypeptide,OTTHUMP00000040880,Wilson disease-associated protein,copper pump 2,copper-transporting ATPase 2
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