Rabbit polyclonal antibody raised against full length recombinant BIRC5.
Recombinant protein corresponding to full length human BIRC5.
Cat, Dog, Human, Mouse, Rat
This antibody is specific to survivin.
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
ChIP (1:50-1:500) Immunocytochemistry (1:50-1:500) Immunofluorescence (1:50-1:500) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:500) Immunoprecipitation (1:1000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
apoptosis inhibitor 4,baculoviral IAP repeat-containing protein 5,survivin variant 3 alpha