CERK polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of CERK on Ceramide Kinase in A-549 cell lysate using CERK polyclonal antibody (Cat # PAB12459).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CERK.
Immunogen
A synthetic peptide corresponding to amino acids 50-150 of human CERK.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to ceramide kinase.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CERK on Ceramide Kinase in A-549 cell lysate using CERK polyclonal antibody (Cat # PAB12459). -
Gene Info — CERK
Entrez GeneID
64781Protein Accession#
Q8TCT0Gene Name
CERK
Gene Alias
DKFZp434E0211, FLJ21430, FLJ23239, KIAA1646, LK4, MGC131878, dA59H18.2, dA59H18.3, hCERK
Gene Description
ceramide kinase
Omim ID
610307Gene Ontology
HyperlinkGene Summary
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM
Other Designations
OTTHUMP00000028554|lipid kinase LK4
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Interactome
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Pathway
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Disease
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Publication Reference
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Substrate specificity of human ceramide kinase.
Wijesinghe DS, Massiello A, Subramanian P, Szulc Z, Bielawska A, Chalfant CE.
Journal of Lipid Research 2005 Dec; 46(12):2706.
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Substrate specificity of human ceramide kinase.
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