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Last updated: 2017/6/25
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DNMT3B polyclonal antibody

  • Catalog # : PAB12444
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant DNMT3B.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 4-101 of human DNMT3B.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is specific to DNMT3b.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Immunofluorescence (1:500)
    Immunoprecipitation (1:1000)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In antiserum
  • Storage Instruction:
  • Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1789
  • Gene Name:
  • DNMT3B
  • Gene Alias:
  • ICF,M.HsaIIIB
  • Gene Description:
  • DNA (cytosine-5-)-methyltransferase 3 beta
  • Gene Summary:
  • CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq
  • Other Designations:
  • DNA MTase HsaIIIB,DNA cytosine-5 methyltransferase 3 beta,DNA methyltransferase HsaIIIB
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