Western blot analysis of human FOXP3 using FOXP3 polyclonal antibody (Cat # PAB12426). Lane 1 : Human CD4+CD25+ PBL, lane 2 : HEK293T transfected with human Foxp3 cDNA, lane 3 : 293/mouse foxp3, lane 4 : 293/empty vector.
Immunohistochemistry (Frozen sections)
Staining of FOXP3 on Healthy thymus from a C57BL/6 mouse using FOXP3 polyclonal antibody (Cat # PAB12426).
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq