GPX3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant GPX3.
Immunogen
Recombinant protein corresponding to full length human GPX3.
Host
Rabbit
Reactivity
Human, Primates, Rat
Form
Liquid
Recommend Usage
Immunocytochemistry (1:200)
Immunofluorescence (1:200)
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of GPX3 on HeLa whole cell extracts using GPX3 polyclonal antibody (Cat # PAB12422).Immunocytochemistry
Immunofluorescence
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Gene Info — GPX3
Entrez GeneID
2878Protein Accession#
P22352Gene Name
GPX3
Gene Alias
GPx-P, GSHPx-3, GSHPx-P
Gene Description
glutathione peroxidase 3 (plasma)
Omim ID
138321Gene Ontology
HyperlinkGene Summary
This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq
Other Designations
extracellular glutathione peroxidase|glutathione peroxidase 3
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Interactome
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Pathway
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Disease
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Publication Reference
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Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferator-activated receptor gamma in human skeletal muscle cells.
Chung SS, Kim M, Youn BS, Lee NS, Park JW, Lee IK, Lee YS, Kim JB, Cho YM, Lee HK, Park KS.
Molecular and Cellular Biology 2009 Jan; 29(1):20.
Application:ELISA, Human, Serum from diabetic patients .
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Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasis.
Yu YP, Yu G, Tseng G, Cieply K, Nelson J, Defrances M, Zarnegar R, Michalopoulos G, Luo JH.
Cancer Research 2007 Sep; 67(17):8043.
Application:WB, IHC-P, Human, Human prostate cancer, 1573, DU145, LNCaP, PC-3 cells.
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Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferator-activated receptor gamma in human skeletal muscle cells.
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