JARID2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of JARID2 in E16 mouse brain lysate using 2 ug/mL of JARID2 polyclonal antibody (Cat # PAB12410).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of JARID2.
Immunogen
A synthetic peptide corresponding to amino acids 1-100 of human JARID2.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody is specific to jumonji.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of JARID2 in E16 mouse brain lysate using 2 ug/mL of JARID2 polyclonal antibody (Cat # PAB12410).Immunocytochemistry
Immunofluorescence
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Gene Info — JARID2
Entrez GeneID
3720Protein Accession#
Q92833Gene Name
JARID2
Gene Alias
JMJ
Gene Description
jumonji, AT rich interactive domain 2
Omim ID
601594Gene Ontology
HyperlinkGene Summary
This gene is an ortholog of the mouse jumonji gene, which encodes a nuclear protein essential for mouse embryogenesis, including neural tube formation. Overexpression of mouse jumonji negatively regulates cell proliferation. The jumonji proteins contain a DNA-binding domain, called an AT-rich interaction domain (ARID), and share regions of similarity with human retinoblastoma-binding protein-2 and the human SMCX protein. [provided by RefSeq
Other Designations
OTTHUMP00000016058|jumonji homolog|jumonji, AT rich interactive domain 2 protein|jumonji-like protein
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Interactome
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Disease
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Publication Reference
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A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.
Shirato H, Ogawa S, Nakajima K, Inagawa M, Kojima M, Tachibana M, Shinkai Y, Takeuchi T.
The Journal of Biological Chemistry 2008 Nov; 284(2):733.
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A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.
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