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Last updated: 2016/12/11
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LRRK2 polyclonal antibody

  • Catalog # : PAB12394
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LRRK2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 2500-2527 of human LRRK2.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Human, Mouse
  • Specificity:
  • This antibody reacts with LRRK2.
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of LRRK2 in 50 ug of crude bovine brain membrane using LRRK2 polyclonal antibody (Cat # PAB12394).
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of LRRK2 in HeLa whole cell lysate (RIPA) using LRRK2 polyclonal antibody (Cat # PAB12394) at 1 : 5,000 dilution.
  • Immunohistochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent CAD cells transfected with human wild-type LRRK2 (1 : 2000) using LRRK2 polyclonal antibody (Cat # PAB12394).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Gene Name:
  • LRRK2
  • Gene Alias:
  • AURA17,DARDARIN,PARK8,RIPK7,ROCO2
  • Gene Description:
  • leucine-rich repeat kinase 2
  • Gene Summary:
  • This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq
  • Other Designations:
  • Parkinson disease (autosomal dominant) 8,augmented in rheumatoid arthritis 17
  • Gene Pathway
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