LYVE1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of LYVE1 in mouse spleen lysate using LYVE1 polyclonal antibody (Cat # PAB12392).
Western Blot (Recombinant protein)
Western blot analysis of LYVE1 in recombinant human protein using LYVE1 polyclonal antibody (Cat # PAB12392).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LYVE1.
Immunogen
A synthetic peptide corresponding to amino acids 250-322 of human LYVE1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of LYVE1 in mouse spleen lysate using LYVE1 polyclonal antibody (Cat # PAB12392).Western Blot (Recombinant protein)
Western blot analysis of LYVE1 in recombinant human protein using LYVE1 polyclonal antibody (Cat # PAB12392). -
Gene Info — LYVE1
Entrez GeneID
10894Protein Accession#
Q9Y5Y7Gene Name
LYVE1
Gene Alias
CRSBP-1, HAR, LYVE-1, XLKD1
Gene Description
lymphatic vessel endothelial hyaluronan receptor 1
Omim ID
605702Gene Ontology
HyperlinkGene Summary
This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq
Other Designations
cell surface retention sequence binding protein-1|extracellular link domain containing 1|extracellular link domain-containing 1|hyaluronic acid receptor
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Interactome
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Disease
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Publication Reference
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Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.
Petrova TV, Karpanen T, Norrmén C, Mellor R, Tamakoshi T, Finegold D, Ferrell R, Kerjaschki D, Mortimer P, Ylä-Herttuala S, Miura N, Alitalo K.
Nature Medicine 2004 Sep; 10(9):974.
Application：IHC, Mouse, Mouse lymphatic vessels.
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A tumor-homing peptide with a targeting specificity related to lymphatic vessels.
Laakkonen P, Porkka K, Hoffman JA, Ruoslahti E.
Nature Medicine 2002 Jul; 8(7):751.
Application：IF, IHC, Human, MDA-MB-435 xenografts.
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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan.
Banerji S, Ni J, Wang SX, Clasper S, Su J, Tammi R, Jones M, Jackson DG.
The Journal of Cell Biology 1999 Feb; 144(4):789.
Application：IF, IHC-P, WB-Tr, Monkey, COS-1 cells, HUVECs, Human tissues.
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Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.
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