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Last updated: 2017/5/21
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MRE11A polyclonal antibody

  • Catalog # : PAB12381
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against MRE11A.
  • Immunogen:
  • Full length human MRE11A.
  • Host:
  • Rabbit
  • Reactivity:
  • Hamster, Human, Mouse
  • Specificity:
  • This antibody is specific to human Mre11.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against MRE11A.
  • Recommend Usage:
  • Immunofluorescence (1:200)
    Western Blot (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In antiserum
  • Storage Instruction:
  • Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of MRE11A on 50 ug of HeLa and MEF lysates, using MRE11A polyclonal antibody (Cat # PAB12381).
  • Immunohistochemistry
  • Immunohistochemistry
  • Staining of MRE11A in the human epidermis using MRE11A polyclonal antibody (Cat # PAB12381).
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 4361
  • Gene Name:
  • MRE11A
  • Gene Alias:
  • ATLD,HNGS1,MRE11,MRE11B
  • Gene Description:
  • MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • AT-like disease,DNA recombination and repair protein,double-strand break repair protein MRE11A,endo/exonuclease Mre11,meiotic recombination 11 homolog A
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