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Last updated: 2017/2/19
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PDE11A polyclonal antibody

  • Catalog # : PAB12366
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against PDE11A.
  • Immunogen:
  • C terminal region of human PDE11A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody selectively detects proteins corresponding to members of the PDE11A sub-family.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Western Blot (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • PDE11A
  • Gene Alias:
  • FLJ23693,MGC133355,MGC133356,PPNAD2
  • Gene Description:
  • phosphodiesterase 11A
  • Gene Summary:
  • The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cAMP and cGMP cyclic nucleotide phosphodiesterase 11A,cyclic nucleotide phosphodiesterase 11A,dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
  • Gene Pathway
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