Western Blot analysis of ROCK2 expression from cell extracts with ROCK2 polyclonal antibody (Cat # PAB12328). Lane 1 : MCF-7 whole cell lysate. Lane 2 : HeLa whole cell lysate. Lane 3 : smmc whole cell lysate. Lane 4 : HT1080 whole cell lysate. Lane 3 : MM453 whole cell lysate.
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq