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Last updated: 2017/3/26
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MMP16 polyclonal antibody

  • Catalog # : PAB12293
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MMP16.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at C-terminus of human MMP16.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 69.5, 52.5
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Identical to the related rat sequence. This antibody recognizes 69.5 KDa for MMP16 long form and 52.5 KDa for short form.
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    Immunohistochemistry (Frozen sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of MMP16 expression from HeLa cell lyate with MMP16 polyclonal antibody (Cat # PAB12293).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of MMP16 on formalin fixed, paraffin embedded rat kidney with MMP16 polyclonal antibody (Cat # PAB12293).
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 4325
  • Gene Name:
  • MMP16
  • Gene Alias:
  • C8orf57,MMP-X2,MT-MMP2,MT-MMP3,MT3-MMP
  • Gene Description:
  • matrix metallopeptidase 16 (membrane-inserted)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq
  • Other Designations:
  • matrix metalloproteinase 16,matrix metalloproteinase 16 (membrane-inserted),membrane-type matrix metalloproteinase 3,membrane-type-3 matrix metalloproteinase
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