HRH3 polyclonal antibody
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Western Blot (Tissue lysate)
Western Blot analysis of HRH3 expression from rat brain tissue lyate with HRH3 polyclonal antibody (Cat # PAB12272).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HRH3.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human HRH3.
Host
Rabbit
Theoretical MW (kDa)
48.6
Reactivity
Human, Mouse, Rat
Specificity
Different to the related rat sequence by two amino acides.
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (0.75 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of HRH3 expression from rat brain tissue lyate with HRH3 polyclonal antibody (Cat # PAB12272). -
Gene Info — HRH3
Entrez GeneID
11255Gene Name
HRH3
Gene Alias
GPCR97, HH3R
Gene Description
histamine receptor H3
Omim ID
604525Gene Ontology
HyperlinkGene Summary
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq
Other Designations
G protein-coupled receptor 97|OTTHUMP00000031459|histamine H3 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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International Union of Pharmacology. XIII. Classification of histamine receptors.
Hill SJ, Ganellin CR, Timmerman H, Schwartz JC, Shankley NP, Young JM, Schunack W, Levi R, Haas HL.
Pharmacological Reviews 1997 Sep; 49(3):253.
Application：Flow Cyt, IHC, WB, Human, Human brains.
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International Union of Pharmacology. XIII. Classification of histamine receptors.
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