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Last updated: 2016/10/16
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CCR6 polyclonal antibody

  • Catalog # : PAB12270
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CCR6.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at N-terminus of human CCR6.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 42.4
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Identical to the related rat and mouse sequence.
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (0.75 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of CCR6 expression from cell and tissue extracts with CCR6 polyclonal antibody (Cat # PAB12270).
    Lane 1 : rat thymus tissue lystae.
    Lane 2 : MCF-7 whole cell lysate.
    Lane 3 : HeLa whole cell lysate.
    Lane 4 : smmc cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of CCR6 on formalin fixed, paraffin embedded rat intestine with CCR6 polyclonal antibody (Cat # PAB12270).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1235
  • Gene Name:
  • CCR6
  • Gene Alias:
  • Gene Description:
  • chemokine (C-C motif) receptor 6
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq
  • Other Designations:
  • G protein-coupled receptor 29,OTTHUMP00000017618,OTTHUMP00000017619,chemokine (C-C) receptor 6,chemokine receptor-like 3,seven-transmembrane receptor, lymphocyte, 22
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