GRIN1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GRIN1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S897 of human GRIN1.
Sequence
RSSKD
Host
Rabbit
Theoretical MW (kDa)
120
Reactivity
Human, Mouse, Rat
Specificity
NMDAR1 (Ab-897) Antibody detects endogenous levels of total NMDAR1 protein.
Form
Liquid
Purification
Immunoaffinity purification
Concentration
1 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunofluorescence
Immunofluorescence staining of methanol-fixed HeLa cells using GRIN1 polyclonal antibody (Cat # PAB12221, Red). -
Gene Info — GRIN1
Entrez GeneID
2902Protein Accession#
Q05586Gene Name
GRIN1
Gene Alias
NMDA1, NMDAR1, NR1
Gene Description
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Omim ID
138249Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
N-methyl-D-aspartate receptor channel, subunit zeta-1|NMDA receptor 1|OTTHUMP00000022678|glutamate [NMDA] receptor subunit zeta 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Group II metabotropic glutamate receptors enhance NMDA receptor currents via a protein kinase C-dependent mechanism in pyramidal neurones of rat prefrontal cortex.
Tyszkiewicz JP, Gu Z, Wang X, Cai X, Yan Z.
The Journal of Physiology 2004 Feb; 554(Pt 3):765.
Application:WB-Ti, Rat, Prefrontal cortex neurones.
-
Group II metabotropic glutamate receptors enhance NMDA receptor currents via a protein kinase C-dependent mechanism in pyramidal neurones of rat prefrontal cortex.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com