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Last updated: 2016/12/4
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GRIN2B polyclonal antibody

  • Catalog # : PAB12211
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GRIN2B.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1474 of human GRIN2B.
  • Sequence:
  • HVYEK
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 190
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • NMDAR2B (Ab-1472) antibody detects endogenous levels of total NMDAR2B protein.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • 1 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of methanol-fixed HeLa cells using GRIN2B polyclonal antibody (Cat # PAB12211, Red).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2904
  • Gene Name:
  • GRIN2B
  • Gene Alias:
  • MGC142178,MGC142180,NMDAR2B,NR2B,hNR3
  • Gene Description:
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Gene Summary:
  • N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq
  • Other Designations:
  • N-methyl-D-aspartate receptor subunit 2B,glutamate receptor subunit epsilon-2
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