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Last updated: 2016/11/27
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TTR polyclonal antibody

  • Catalog # : PAB1221
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant TTR.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 21-147 of human TTR.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:1800)
    Immunoprecipitation (1 ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Immunoblot analysis of cell lysates. Lane 1 : rat liver, lane 2 : 293T cell lysates transfected with GFP-Prealbumin.
  • Immunoprecipitation
  • Application Image
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 7276
  • Gene Name:
  • TTR
  • Gene Alias:
  • HsT2651,PALB,TBPA
  • Gene Description:
  • transthyretin
  • Gene Summary:
  • This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq
  • Other Designations:
  • prealbumin, amyloidosis type I,thyroxine-binding prealbumin
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