Immunoblot analysis of cell lysates. Lane 1 : HeLa cell lysate. Lane 2 : A-431 cell lysate. * For Western blots, incubate membrane with diluted antibody in 5% w/v BSA , 1X TBS , 0.1% Tween-20 at 4°C with gentle shaking , overnight.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq