Lyve1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Lyve1.
Immunogen
A synthetic peptide corresponding to amino acids 250-318 of mouse Lyve1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Flow Cytometry (1:25)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of Lyve1 in mouse spleen lysate using Lyve1 polyclonal antibody (Cat # PAB12131). ECL Western blot analysis overnight.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of Lyve1 in endothelial cells of human lung blood vessels using Lyve1 polyclonal antibody (Cat # PAB12131). Note presence of RBCs within vessel lumen.Immunohistochemistry
Detection of Lyve1 in endothelial cells of human bladder vasculature using Lyve1 polyclonal antibody (Cat # PAB12131).Immunohistochemistry
Detection of Lyve1 in endothelial cells of human lung blood vessels using Lyve1 polyclonal antibody (Cat # PAB12131).Flow Cytometry
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Gene Info — Lyve1
Entrez GeneID
114332Protein Accession#
Q8BHC0Gene Name
Lyve1
Gene Alias
1200012G08Rik, Crsbp-1, Lyve-1, Xlkd1
Gene Description
lymphatic vessel endothelial hyaluronan receptor 1
Gene Ontology
HyperlinkOther Designations
cell surface retention sequence binding protein-1|extra cellular link domain-containing 1|lymphatic vessel endothelial HA receptor-1|lymphatic vessel endothelial HA recptor-1
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Publication Reference
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Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.
Petrova TV, Karpanen T, Norrmén C, Mellor R, Tamakoshi T, Finegold D, Ferrell R, Kerjaschki D, Mortimer P, Ylä-Herttuala S, Miura N, Alitalo K.
Nature Medicine 2004 Sep; 10(9):974.
Application:IHC, Mouse, Mouse lymphatic vessels.
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A tumor-homing peptide with a targeting specificity related to lymphatic vessels.
Laakkonen P, Porkka K, Hoffman JA, Ruoslahti E.
Nature Medicine 2002 Jul; 8(7):751.
Application:IF, IHC, Human, MDA-MB-435 xenografts.
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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan.
Banerji S, Ni J, Wang SX, Clasper S, Su J, Tammi R, Jones M, Jackson DG.
The Journal of Cell Biology 1999 Feb; 144(4):789.
Application:IF, IHC-P, WB-Tr, Monkey, COS-1 cells, HUVECs, Human tissues.
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Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.
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