Chicken polyclonal antibody raised against recombinant VIM.
Immunogen:
Recombinant protein corresponding to human VIM.
Host:
Chicken
Reactivity:
Human, Mouse, Rat
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Recommend Usage:
Immunofluorescence (1:5000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:150) The optimal working dilution should be determined by the end user.
Storage Buffer:
In buffer containing 5 mM sodium azide
Storage Instruction:
Store at 4°C for short term. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract