Rabbit polyclonal antibody raised against synthetic peptide of OS9.
A synthetic peptide corresponding to amino acids 300-400 of human OS9.
This antibody is specific to isoforms 1 and 2 of human OS-9.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Immunofluorescence (0.2-1 ug/mL) Immunohistochemistry (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:250) Western Blot (0.2-1 ug/mL) The optimal working dilution should be determined by the end user.
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.01% sodium azide)
Store at 4°C. Do not freeze.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq