PDK1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of PDK1 in human heart lysate with PDK1 polyclonal antibody at 2 ug/mL (Cat # PAB12077).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDK1.
Immunogen
A synthetic peptide corresponding to amino acids 350-436 of human PDK1.
Host
Rabbit
Reactivity
Chicken, Human, Mouse, Rat
Specificity
This antibody is specific to PDK1.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of PDK1 in human heart lysate with PDK1 polyclonal antibody at 2 ug/mL (Cat # PAB12077). -
Gene Info — PDK1
Entrez GeneID
5163Protein Accession#
Q15118Gene Name
PDK1
Gene Alias
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Gene Description
pyruvate dehydrogenase kinase, isozyme 1
Omim ID
602524Gene Ontology
HyperlinkGene Summary
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. [provided by RefSeq
Other Designations
mitochondrial pyruvate dehydrogenase kinase isoenzyme 1|pyruvate dehydrogenase kinase, isoenzyme 1
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Interactome
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Pathway
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Disease
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