PINK1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PINK1 in, Lane1 : control, Lane2 : ES cell (mouse) Mitochondria (20 ug), Lane3 : ES cell (mouse) cytosol (20 ug), Lane4 : ES cell (mouse) nuclear (20 ug) as negative control with PINK1 polyclonal antibody (Cat # PAB12072).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PINK1.
Immunogen
A synthetic peptide corresponding to amino acids 1-50 of human PINK1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of PINK1 in, Lane1 : control, Lane2 : ES cell (mouse) Mitochondria (20 ug), Lane3 : ES cell (mouse) cytosol (20 ug), Lane4 : ES cell (mouse) nuclear (20 ug) as negative control with PINK1 polyclonal antibody (Cat # PAB12072). -
Gene Info — PINK1
Entrez GeneID
65018Gene Name
PINK1
Gene Alias
BRPK, FLJ27236, PARK6
Gene Description
PTEN induced putative kinase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq
Other Designations
OTTHUMP00000002881|protein kinase BRPK|serine/threonine-protein kinase PINK1
-
Interactome
-
Disease
-
Publication Reference
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner N, Treske B, Paquet D, Holmström K, Schiesling C, Gispert S, Carballo-Carbajal I, Berg D, Hoepken HH, Gasser T, Krüger R, Winklhofer KF, Vogel F, Reichert AS, Auburger G, Kahle PJ, Schmid B, Haass C.
Journal of Neuroscience 2007 Nov; 27(45):12413.
Application：WB-Tr, Human, HeLa cells.
-
Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe.
Meijer M, Karimi-Busheri F, Huang TY, Weinfeld M, Young D.
The Journal of Biological Chemistry 2002 Feb; 277(6):4050.
Application：WB-Re, Recombinant proteins.
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com