Western blot analysis of PINK1 in, Lane1 : control, Lane2 : ES cell (mouse) Mitochondria (20 ug), Lane3 : ES cell (mouse) cytosol (20 ug), Lane4 : ES cell (mouse) nuclear (20 ug) as negative control with PINK1 polyclonal antibody (Cat # PAB12072).
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq