PLTP polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of PLTP in human (Lane 1) and mouse brain (Lane 2) lysates with PLTP polyclonal antibody (Cat # PAB12070).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PLTP.
Immunogen
A synthetic peptide corresponding to human PLTP.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody is specific to Phospholipid Transfer Protein (PLTP).
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In antiserum (0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of PLTP in human (Lane 1) and mouse brain (Lane 2) lysates with PLTP polyclonal antibody (Cat # PAB12070). -
Gene Info — PLTP
Entrez GeneID
5360Gene Name
PLTP
Gene Alias
HDLCQ9
Gene Description
phospholipid transfer protein
Omim ID
172425Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000031678|lipid transfer protein II
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Interactome
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Pathway
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Disease
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Publication Reference
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Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex.
He Y, Greene DJ, Kinter M, Morton RE.
Journal of Lipid Research 2008 Jul; 49(7):1529.
Application：WB, Human, Human plasma.
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Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression.
Valenta DT, Ogier N, Bradshaw G, Black AS, Bonnet DJ, Lagrost L, Curtiss LK, Desrumaux CM.
Arteriosclerosis, Thrombosis, and Vascular Biology 2006 Jul; 26(7):1572.
Application：IHC-Fr, Mouse, Mouse aortic sinus sections.
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Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells.
Desrumaux CM, Mak PA, Boisvert WA, Masson D, Stupack D, Jauhiainen M, Ehnholm C, Curtiss LK.
Journal of Lipid Research 2003 Aug; 44(8):1453.
Application：IF, IHC-P, WB, Human, Human carotid endarterectomy sections, Human macrophages, THP-1 cells.
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Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex.
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