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Last updated: 2016/11/27
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POT1 polyclonal antibody

  • Catalog # : PAB12064
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of POT1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 200-300 of human POT1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to POT1.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris-glycine, 150 mM NaCl
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of POT1 in HeLa nuclear extracts (25 ug) with POT1 polyclonal antibody (Cat # PAB12064).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • POT1
  • Gene Alias:
  • DKFZp586D211,hPot1
  • Gene Description:
  • POT1 protection of telomeres 1 homolog (S. pombe)
  • Gene Summary:
  • This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq
  • Other Designations:
  • POT1-like telomere end-binding protein,protection of telomeres 1
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