RAD9A polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of RAD9A in U-2 OS cell lysate with RAD9A polyclonal antibody (Cat # PAB12050).
-
Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant RAD9A.
Immunogen
Recombinant protein corresponding to full length human RAD9A.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Immunohistochemistry (1:800)
Western Blot (1:1000-1:1500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of RAD9A in U-2 OS cell lysate with RAD9A polyclonal antibody (Cat # PAB12050).Immunohistochemistry
-
Gene Info — RAD9A
Entrez GeneID
5883Gene Name
RAD9A
Gene Alias
RAD9
Gene Description
RAD9 homolog A (S. pombe)
Omim ID
603761Gene Ontology
HyperlinkGene Summary
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. [provided by RefSeq
Other Designations
RAD9 homolog|cell cycle checkpoint control protein
-
Interactome
-
Disease
-
Publication Reference
-
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage.
Medhurst AL, Warmerdam DO, Akerman I, Verwayen EH, Kanaar R, Smits VA, Lakin ND.
Journal of Cell Science 2008 Dec; 121(Pt 23):3933.
Application：WB, Human, HeLa, U-2 OS cells.
-
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.
Chen MJ, Lin YT, Lieberman HB, Chen G, Lee EY.
The Journal of Biological Chemistry 2001 May; 276(19):16580.
Application：IP-WB, WB-Ce, WB-Tr, Human, T24, NBS, A-T cells.
-
A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene.
Lieberman HB, Hopkins KM, Nass M, Demetrick D, Davey S.
PNAS 1996 Nov; 93(24):13890.
-
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com