SLC2A9 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC2A9.
Immunogen
A synthetic peptide corresponding to amino acids 500-550 of human SLC2A9.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SLC2A9 in human kidney membrane with SLC2A9 polyclonal antibody (Cat # PAB12030). -
Gene Info — SLC2A9
Entrez GeneID
56606Protein Accession#
Q9NRM0Gene Name
SLC2A9
Gene Alias
GLUT9, GLUTX, UAQTL2, URATv1
Gene Description
solute carrier family 2 (facilitated glucose transporter), member 9
Omim ID
606142Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
human glucose transporter-like protein-9|solute carrier family 2, member 9 protein|urate voltage-driven efflux transporter 1
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Interactome
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Disease
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Publication Reference
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Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans.
Anzai N, Ichida K, Jutabha P, Kimura T, Babu E, Jin CJ, Srivastava S, Kitamura K, Hisatome I, Endou H, Sakurai H.
The Journal of Biological Chemistry 2008 Oct; 283(40):26834.
Application:IHC, Frog, Xenopus Oocytes.
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SLC2A9--a fructose transporter identified as a novel uric acid transporter.
Le MT, Shafiu M, Mu W, Johnson RJ.
Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant 2008 Sep; 23(9):2746.
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SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.
Vitart V, Rudan I, Hayward C, Gray NK, Floyd J, Palmer CN, Knott SA, Kolcic I, Polasek O, Graessler J, Wilson JF, Marinaki A, Riches PL, Shu X, Janicijevic B, Smolej-Narancic N, Gorgoni B, Morgan J, Campbell S, Biloglav Z, Barac-Lauc L, Pericic M, Klaric IM, Zgaga L, Skaric-Juric T, Wild SH, Richardson WA, Hohenstein P, Kimber CH, Tenesa A, Donnelly LA, Fairbanks LD, Aringer M, McKeigue PM, Ralston SH, Morris AD, Rudan P, Hastie ND, Campbell H, Wright AF.
Nature Genetics 2008 Apr; 40(4):437.
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Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans.
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