Trpm2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Trpm2.
Immunogen
A synthetic peptide corresponding to amino acids 1200-1300 of mouse Trpm2.
Host
Rabbit
Reactivity
Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (30% glycerol, 0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of Trpm2 in mouse brain membrane lysates with Trpm2 polyclonal antibody (Cat # PAB11991). -
Gene Info — Trpm2
Entrez GeneID
28240Protein Accession#
Q91YD4Gene Name
Trpm2
Gene Alias
9830168K16Rik, C79133, LTRPC2, TRPC7, Trp7, Trrp7
Gene Description
transient receptor potential cation channel, subfamily M, member 2
Gene Ontology
HyperlinkGene Summary
subfamily M
Other Designations
transient receptor potential channel 7|transient receptor protein 7
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Publication Reference
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TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.
Zhang W, Hirschler-Laszkiewicz I, Tong Q, Conrad K, Sun SC, Penn L, Barber DL, Stahl R, Carey DJ, Cheung JY, Miller BA.
American Journal of Physiology. Cell Physiology 2006 Apr; 290(4):C1146.
Application:IF, WB-Tr, Human, U937-ecoR cells.
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A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death.
Zhang W, Chu X, Tong Q, Cheung JY, Conrad K, Masker K, Miller BA.
The Journal of Biological Chemistry 2003 May; 278(18):16222.
Application:IP, WB-Tr, Human, HEK 293T, TF-1 cells.
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TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.
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