WNK1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of WNK1.
Immunogen
A synthetic peptide corresponding to C-terminus of human WNK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
The specificity of this antibody is for WNK1.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — WNK1
Entrez GeneID
65125Gene Name
WNK1
Gene Alias
KDP, KIAA0344, PHA2C, PRKWNK1, PSK
Gene Description
WNK lysine deficient protein kinase 1
Gene Ontology
HyperlinkGene Summary
The WNK1 gene encodes a cytoplasmic serine-threonine kinase expressed in distal nephron.[supplied by OMIM
Other Designations
OTTHUMP00000115370|kinase deficient protein|prostate-derived sterile 20-like kinase|protein kinase, lysine deficient 1|serine/threonine-protein kinase WNK1
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Interactome
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Disease
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Publication Reference
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WNK1 kinase isoform switch regulates renal potassium excretion.
Wade JB, Fang L, Liu J, Li D, Yang CL, Subramanya AR, Maouyo D, Mason A, Ellison DH, Welling PA.
PNAS 2006 May; 103(22):8558.
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WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension.
Xu BE, Lee BH, Min X, Lenertz L, Heise CJ, Stippec S, Goldsmith EJ, Cobb MH.
Cell Research 2005 Jan; 15(1):6.
Application:WB-Ce, Human, Mouse, CHO, DCT, HeLa, HEK 293, HME31, HME50, HT-29, INS-1, MCF-7, MDA-MB-231, ME16C, NIH/3T3, SW480,SWNPC2 cells.
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WNK1 kinase isoform switch regulates renal potassium excretion.
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