XAGE1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human XAGE1.
Immunogen
A synthetic peptide corresponding to an internal sequence within human XAGE1.
Host
Rabbit
Theoretical MW (kDa)
20
Reactivity
Human
Form
Liquid
Purity
Unpurified.
Recommend Usage
Immunoprecipitation (1:10-1:500)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In whole antisera (0.09% sodium azide).
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of XAGE1 on purified His-XAGE1 (100 ug) with XAGE1 polyclonal antibody (Cat # PAB11978).Immunoprecipitation
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Gene Info — XAGE1D
Entrez GeneID
9503Protein Accession#
Q9HD64Gene Name
XAGE1D
Gene Alias
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Gene Description
X antigen family, member 1D
Omim ID
300289Gene Ontology
HyperlinkGene Summary
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to the use of an alternative transcription start site and an alternative translation initiation codon, results in multiple variants that encode different isoforms. [provided by RefSeq
Other Designations
G antigen, family D, 2|OTTHUMP00000042367
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Gene Info — XAGE1E
Entrez GeneID
653067Protein Accession#
Q9HD64Gene Name
XAGE1E
Gene Alias
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Gene Description
X antigen family, member 1E
Gene Ontology
HyperlinkGene Summary
XAGE1E is 1 of 5 copies of the XAGE1 gene (see XAGE1D; MIM 300289) (Chen et al., 2006 [PubMed 16382448]).[supplied by OMIM
Other Designations
X antigen family member 1E|xage-1 p16
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Publication Reference
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Characterization of overlapping XAGE-1 transcripts encoding a cancer testis antigen expressed in lung, breast, and other types of cancers.
Egland KA, Kumar V, Duray P, Pastan I.
Molecular Cancer Therapeutics 2002 May; 1(7):441.
Application:WB-Tr, Human, HEK 293T cells.
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XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma.
Liu XF, Helman LJ, Yeung C, Bera TK, Lee B, Pastan I.
Cancer Research 2000 Sep; 60(17):4752.
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Novel genes in the PAGE and GAGE family of tumor antigens found by homology walking in the dbEST database.
Brinkmann U, Vasmatzis G, Lee B, Pastan I.
Cancer Research 1999 Apr; 59(7):1445.
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Characterization of overlapping XAGE-1 transcripts encoding a cancer testis antigen expressed in lung, breast, and other types of cancers.
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