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Last updated: 2017/12/10
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CASP8AP2 polyclonal antibody

  • Catalog # : PAB11945
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CASP8AP2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1253-1268 of human CASP8AP2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody recognizes human and mouse FLASH (220 kD). This sequence differs by one amino acid from that of mouse.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 9994
  • Gene Name:
  • CASP8AP2
  • Gene Alias:
  • CED-4,FLASH,FLJ11208,KIAA1315,RIP25
  • Gene Description:
  • caspase 8 associated protein 2
  • Gene Summary:
  • This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein
  • Other Designations:
  • CASP8 associated protein 2,FLASH homolog RIP25,FLICE associated huge,FLICE-associated huge protein,human FLASH
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