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Last updated: 2016/10/16
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THRB polyclonal antibody

  • Catalog # : PAB11824
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of THRB.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 31-50 of human THRB.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 55
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • Lot specific
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-Fixed Paraffin-Embedded Sections) staining of human colon with THRB polyclonal antibody (Cat # PAB11824).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 7068
  • Gene Name:
  • THRB
  • Gene Alias:
  • Gene Description:
  • thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
  • Gene Summary:
  • The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161044,avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2,oncogene ERBA2,thyroid hormone receptor beta 1,thyroid hormone receptor beta isoform,thyroid hormone receptor, beta
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