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Last updated: 2016/11/27
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SNC polyclonal antibody

  • Catalog # : PAB11819
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SNC.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human SNC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 14
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • Lot specific
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of SNCA/SNCB/SNCG on formalin fixed, paraffin embedded human brain with SNC polyclonal antibody (Cat # PAB11819).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 6622
  • Gene Name:
  • SNCA
  • Gene Alias:
  • MGC110988,NACP,PARK1,PARK4,PD1
  • Gene Description:
  • synuclein, alpha (non A4 component of amyloid precursor)
  • Gene Summary:
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
  • Gene Information
  • Entrez GeneID:
  • 6620
  • Gene Name:
  • SNCB
  • Gene Alias:
  • -
  • Gene Description:
  • synuclein, beta
  • Other Designations:
  • beta-synuclein
  • Gene Information
  • Entrez GeneID:
  • 6623
  • Gene Name:
  • SNCG
  • Gene Alias:
  • BCSG1,SR
  • Gene Description:
  • synuclein, gamma (breast cancer-specific protein 1)
  • Gene Summary:
  • Summary: This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020013,breast cancer-specific protein 1,persyn,synoretin,synuclein, gamma (breast cancer-specific gene 1)
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