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Last updated: 2017/4/23
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GRIK2/GRIK3 polyclonal antibody

  • Catalog # : PAB11667
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GRIK2/GRIK3.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human GRIK2/GRIK3.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 100
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • Lot specific
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-Fixed Paraffin-Embedded Sections) staining of human brain with GRIK2/GRIK3 polyclonal antibody (Cat # PAB11667).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 2898
  • Gene Name:
  • GRIK2
  • Gene Alias:
  • EAA4,GLR6,GLUK6,GLUR6,MGC74427,MRT6
  • Gene Description:
  • glutamate receptor, ionotropic, kainate 2
  • Gene Summary:
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017949,bA487F5.1,excitatory amino acid receptor 4,glutamate receptor 6
  • Gene Information
  • Entrez GeneID:
  • 2899
  • Gene Name:
  • GRIK3
  • Gene Alias:
  • EAA5,GLR7,GLUR7,GluR7a
  • Gene Description:
  • glutamate receptor, ionotropic, kainate 3
  • Gene Summary:
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000004360,dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)),excitatory amino acid receptor 5,glutamate receptor 7
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