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DYSF polyclonal antibody

  • Catalog # : PAB11642
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DYSF.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human DYSF.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 231
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • Lot specific
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of DYSF on formalin fixed, paraffin embedded human skeletal muscle with DYSF polyclonal antibody (Cat # PAB11642).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 8291
  • Gene Name:
  • DYSF
  • Gene Alias:
  • FER1L1,FLJ00175,FLJ90168,LGMD2B
  • Gene Description:
  • dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
  • Gene Summary:
  • The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • dysferlin,dystrophy-associated fer-1-like 1
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