TRPV3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TRPV3.
Immunogen
A synthetic peptide corresponding to amino acids 762-773 near C-terminus of human TRPV3.
Sequence
C-NKIQDSSRNNSK
Host
Goat
Theoretical MW (kDa)
90.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRPV3
Entrez GeneID
162514Protein Accession#
NP_659505.1Gene Name
TRPV3
Gene Alias
VRL3
Gene Description
transient receptor potential cation channel, subfamily V, member 3
Omim ID
607066Gene Ontology
HyperlinkGene Summary
This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. [provided by RefSeq
Other Designations
vanilloid receptor 3|vanilloid receptor-related osmotically activated channel protein
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Interactome
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Publication Reference
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TRPV3 is a calcium-permeable temperature-sensitive cation channel.
Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE.
Nature 2002 Jul; 418(6894):181.
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TRPV3 is a calcium-permeable temperature-sensitive cation channel.
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