RASSF3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RASSF3.
Immunogen
A synthetic peptide corresponding to human RASSF3.
Sequence
CKPPQTSPNSGK
Host
Goat
Theoretical MW (kDa)
27.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
RASSF3 polyclonal antibody (Cat # PAB11576) (0.5 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RASSF3
Entrez GeneID
283349Protein Accession#
NP_835463.1Gene Name
RASSF3
Gene Alias
MGC119194, MGC119195, MGC119197, RASSF5
Gene Description
Ras association (RalGDS/AF-6) domain family member 3
Omim ID
607019Gene Ontology
HyperlinkGene Summary
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM
Other Designations
Ras association (RalGDS/AF-6) domain family 3
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Interactome
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Publication Reference
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RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1.
Tommasi S, Dammann R, Jin SG, Zhang XF, Avruch J, Pfeifer GP.
Oncogene 2002 Apr; 21(17):2713.
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RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1.
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