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Last updated: 2016/12/4
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OTUB1 polyclonal antibody

  • Catalog # : PAB11566
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of OTUB1.
  • Immunogen:
  • A synthetic peptide corresponding to human OTUB1.
  • Sequence:
  • C-YKEYAEDDNIYQQK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 31.3
  • Reactivity:
  • Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.03-0.1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • OTUB1 polyclonal antibody (Cat # PAB11566) (0.05 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • OTUB1
  • Gene Alias:
  • FLJ20113,FLJ40710,HSPC263,MGC111158,MGC4584,OTB1,OTU1
  • Gene Description:
  • OTU domain, ubiquitin aldehyde binding 1
  • Gene Summary:
  • The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • OTU-domain Ubal-binding 1,otubain 1,ubiquitin-specific protease otubain 1
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