NTF4 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NTF4.
Immunogen
A synthetic peptide corresponding to human NTF4.
Sequence
FETRCKADNAEEG
Host
Goat
Theoretical MW (kDa)
22.4
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
NTF4 polyclonal antibody (Cat # PAB11560) (0.1 ug/mL) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NTF4
Entrez GeneID
4909Protein Accession#
NP_006170.1Gene Name
NTF4
Gene Alias
NT-4/5, NT4, NT5, NTF5
Gene Description
neurotrophin 4
Omim ID
162662Gene Ontology
HyperlinkGene Summary
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq
Other Designations
neurotrophic factor 4|neurotrophic factor 5|neurotrophin 5|neurotrophin 5 (neurotrophin 4/5)
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Interactome
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Pathway
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Disease
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Publication Reference
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A novel function of differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression.
Nalbandian A, Pang AL, Rennert OM, Chan WY, Ravindranath N, Djakiew D.
Differentiation 2005 Oct; 3(8):385.
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Presence and localization of neurotrophins and neurotrophin receptors in rat lacrimal gland.
Ghinelli E, Johansson J, Rios JD, Chen LL, Zoukhri D, Hodges RR, Dartt DA.
Investigative Ophthalmology & Visual Science 2003 Aug; 44(8):3352.
Application:IF, IHC-Fr, WB-Ti, Rat, Brains, Lacrimal gland tissue.
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A novel function of differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression.
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