ABCC12 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ABCC12 polyclonal antibody (Cat # PAB11555) (3.8 ug/mL) staining of paraffin embedded human testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ABCC12.
Immunogen
A synthetic peptide corresponding to internal region of human ABCC12.
Sequence
GDLHCEIRDQET
Host
Goat
Theoretical MW (kDa)
94.7, 93, 92.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-3.8 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ABCC12 polyclonal antibody (Cat # PAB11555) (3.8 ug/mL) staining of paraffin embedded human testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCC12
Entrez GeneID
94160Protein Accession#
NP_150229.2Gene Name
ABCC12
Gene Alias
MGC27071, MRP9
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Omim ID
607041Gene Ontology
HyperlinkGene Summary
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq
Other Designations
ATP-binding cassette protein C12|ATP-binding cassette transporter sub-family C member 12|OTTHUMP00000164186|multidrug resistance-associated protein 9
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Pathway
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Disease
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Publication Reference
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Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.
Yabuuchi H, Shimizu H, Takayanagi S, Ishikawa T.
Biochemical and Biophysical Research Communications 2001 Nov; 288(4):933.
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Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.
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