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Last updated: 2017/6/25
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KCNQ4 polyclonal antibody

  • Catalog # : PAB11544
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of KCNQ4.
  • Immunogen:
  • A synthetic peptide corresponding to human KCNQ4.
  • Sequence:
  • C-DKGPSDAEVVDE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 77.1, 71.2
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:4000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • KCNQ4 polyclonal antibody (Cat # PAB11544) (2 ug/mL) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9132
  • Protein Accession#:
  • NP_004691.2;NP_751895.1
  • Gene Name:
  • KCNQ4
  • Gene Alias:
  • DFNA2,KV7.4
  • Gene Description:
  • potassium voltage-gated channel, KQT-like subfamily, member 4
  • Gene Summary:
  • The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000009219,potassium channel KQT-like 4,potassium voltage-gated channel KQT-like protein 4
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