CLEC1B polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of CLEC1B.
Immunogen
A synthetic peptide corresponding to human CLEC1B.
Sequence
KGHKCSPCDTNWRY
Host
Goat
Theoretical MW (kDa)
26.6, 23.1
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CLEC1B polyclonal antibody (Cat # PAB11512) (1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CLEC1B
Entrez GeneID
51266Protein Accession#
NP_001092901.1;NP_057593.3Gene Name
CLEC1B
Gene Alias
1810061I13Rik, CLEC2, CLEC2B, PRO1384, QDED721
Gene Description
C-type lectin domain family 1, member B
Omim ID
606783Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM
Other Designations
C-type lectin-like receptor-2
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Interactomes
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Diseases
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Publication Reference
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Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.
Suzuki-Inoue K, Kato Y, Inoue O, Kaneko MK, Mishima K, Yatomi Y, Yamazaki Y, Narimatsu H, Ozaki Y.
The Journal of Biological Chemistry 2007 Sep; 282(36):25993.
Application:Flow Cyt, Mouse, CHO cells .
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Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.
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